产品货号:
Z14213
中文名称:
EI24抗体
英文名称:
Anti-EI24 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-EI24 Antibody |
指标别名 | EI24,etoposide induced 2.4 mRNA,p53 induced gene 8 protein,p53-induced factor Ei24,PIG8,TP53I8 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC |
基因名称 | EI24 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | EI24 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human EI24.The immunogen is located within the last 50 amino acids of EI24. |
计算分子量 | 39kDa |
成分 | EI24 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | EI24 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | The etoposide-induced 24 (EI24) protein is an immediate-early induction target of p53-mediated apoptosis and functions as a tumor suppressor.EI24 contains six transmembrane domains and is localized to the endoplasmic reticulum (ER).It binds to Bcl-2 and may contribute to apoptosis by modulating the activity and function of Bcl-2.EI24 is highly mutated in aggressive breast cancers and its loss in breast cancer tissue correlates with tumor invasiveness.Similar findings in invasive cervical carcinoma suggest that EI24 may be a promising therapeutic target in the treatment of invasive cancer. |
Uniprot ID | O14681 |
基因名全称 | Etoposide induced 2.4 mRNA |
蛋白名全称 | Etoposide induced 2.4 mRNA |
推荐稀释比 | EI24 antibody can be used for detection of EI24 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.Antibody validated:Western Blot in rat samples and Immunohistochemistry in rat samples.All other applications and species not yet tested. |
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